Modvigil could minimize the performance of warfarin, an anticoagulant medication. This can elevate the risk of blood clots and stroke. Regular monitoring of blood clotting parameters is vital when making use of these drugs together.

Dose changes could possibly be necessary for sufferers having these and equivalent medicines (PROVIGIL® 2007). As the performance of steroidal contraceptives may very well be reduced when taken concurrently with modafinil, added or substitute ways of contraception need to be utilized throughout cure with modafinil and for 1 month after discontinuation of modafinil therapy (Robertson et al 2002b; PROVIGIL® 2007).

Also tell your medical doctor For those who have any new recognizing or breakthrough bleeding, mainly because these could be signs that the birth Handle is not Operating perfectly.

itraconazole will improve the amount or result of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Stay away from or substitute another drug for these prescription drugs when doable. Consider for lack of therapeutic impact if medication need to be coadministered. Regulate dose In keeping with prescribing information if essential.

Este demonstrat că utilizarea de Modafinil nu are efecte secundare semnificative. În cazul apariției unor efecte secundare ușoare, de obicei este suficient să reduci doza și vei fin din nou perfect în regulă, pregătit pentru performanțe maxime.

Modafinil appeared to create a concentration-similar suppression of CYP2C9 exercise, therefore suggesting likely for CYP2C9 inhibition; warning if medicines which have a narrow therapeutic index

modafinil will minimize the level Modalert 200 or effect of iobenguane I 131 by Other (see comment). Stay away from or Use Alternate Drug. Depending on the system of action of iobenguane, medication that minimize catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and so, reduce iobenguane efficacy.

modafinil will increase the degree or outcome of pantoprazole by influencing hepatic enzyme CYP2C19 metabolism. Minor/Significance Mysterious. Internet effect on pantoprazole actions unidentified as a consequence of opposing results of CYP450 enzymes; watch

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elvitegravir/cobicistat/emtricitabine/tenofovir DF increases amounts of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

acetazolamide will enhance the degree or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.

The above details is furnished for typical informational and educational functions only. Specific options may perhaps vary and formulary info adjustments. Speak to the relevant prepare company for quite possibly the most current information.

Modvigil could communicate with selected antidepressant medications, like fluoxetine and sertraline. Combining these drugs can improve the possibility of serotonin syndrome, a significant ailment that can cause signs like agitation, hallucinations, swift heartbeat, and significant system temperature.